Jeremiah J. Gassensmith

Biography

2001 Joined the Laboratory of Joseph J. Gajewski at Indiana University as an undergraduate researcher.

2002 Interned at Eli Lilly working on the synthesis of Lysergic Acid derivatives using tandem photocycliation-cycloaddition reactions

2004 Graduated Indiana University with honors in chemistry. Honors thesis: Kinetic isotope effects of addition of Grignard reagents to benzylic aldehydes


2005 Worked at Eli Lilly as an analytical chemist

2006 Joined the Laboratory of Bradley D. Smith at The University of Notre Dame as a graduate researcher.

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Research Interests

My research interests lie within the field of supramolecular chemistry. I am currently focused on the synthesis of inclusion complexes with fluorescent properties with applications ranging from materials and nano devices to the forté of our lab, bioimaging. While our group principally focuses on the biological aspect of these systems, i.e. their use as probes for imaging in vivo, my interest and research is focused on understanding the underlying physical mechanisms as well as designing systems which work more efficiently in different media and have variable fluorescent properties depending upon their local environment.

I am also actively involved in crystallography and the solid state structural analysis of supramolecular complexes. I tend to be actively trying to solve at least one crystal at any given moment.

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Recent Papers

Jeremiah J. Gassensmith, Easwaran Arunkumar, Lorna Barr, Jeffrey M. Baumes, Kristy M. DiVittorio, James R. Johnson, Bruce C. Noll, Bradley D. Smith, J. Am. Chem. Soc., 2007 129, 15054 -15059. Self-Assembly of Fluorescent Inclusion Complexes in Competitive Media Including the Interior of Living Cells. ♦Featured in C&E News: December 10, 2007

Link

Jeremiah J. Gassensmith, Jung-Jae Lee, Bruce C. Noll, Bradley D. Smith, New J. Chem, 2008, 32, 843-847. Crossing the Threshold from Substitution to Elimination with a Bifuncational Macrocycle. ♦Special Edition in honor of Prof. Jerry Atwood

Link

Jeremiah J. Gassensmith, Lorna Barr, Jeffrey M. Baumes, Agelina Paek, Anh Nguyen and Bradley D. Smith. Org. Lett. 2008, 10, 3343-3346 Synthesis and Photophysical Investigation of Squaraine Rotaxanes by “Clicked Capping”

Link

Na Fu, Jeremiah J. Gassensmith, Bradley D. Smith, Supramol. Chem., 2008, Accepted, in press. Effect of Stopper Size on Squaraine Rotaxane Stability. ♦Invited article for the 3rd Joint ISMSC conference

Jeremiah J. Gassensmith,Easwaran Arunkumar, and Bradley D. Smith. Dye Encapsulation in "Molecular Encapsulation: Reactions in Constrained Systems." Wiley Press, 2009. Accepted, in press.

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Presentations

Discovery of a bifunctional macrocycle: Guest dependent reactivity

  • Presented On: 09/10/2006
  • Event: 232nd ACS National Meeting
  • Location: San Fransisco, CA
  • Authors: Jeremiah J. Gassensmith, Bradley D. Smith

Mix and play squaraine-rotaxanes

  • Presented On: 08/19/2007
  • Event: 234th ACS National Meeting
  • Location: Boston, MA
  • Authors: Jeremiah J. Gassensmith, Bradley D. Smith

Fluorescent rotaxanes by self-assembly and covalent caputre

  • Presented On: 07/22/2008
  • Event: 3rd Joint ISMSC
  • Location: Las Vegas, NV
  • Authors: Jeremiah J. Gassensmith, Bradley D. Smith

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Contact Information

Lab Advisor(s)

Schools

  • Indiana University, Bloomington
    BS, Chemistry, Honors
    Year(s): 2000-2004